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valves in the vetus. In the preface to the readerhe says that in ille Coui se of his Work he has made severat discoveries capable of Wide application in medicine. This is a pregnant phrasein utere of the faet iliat he who Wroto it is ille discoverer of valves in the vetus. Manifestly the phrase is too vague, of iοο Wide an application, to Waylay us. The ni si direct referetice to this epochai discovery is mund in the folloning sfa-tement of Vesalius :